RNA Details
Disease Name
acute lung injury
Tissue
lung
RNA Symbol
Timp1
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
BAL; Immunohistochemistry; Neutrophil chemotaxis assay etc.
Target
NA
Pathway
NA
PubMed ID
Title
Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice
Year
2005
Function
"TIMP-1 contributes significantly to the regulation of acute lung injury, functioning to limit inflammation and lung permeability."